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Non-coding RNA transcription: turning on neighbours

Even though less than 2% of the mammalian genome encodes proteins, a significant fraction can be transcribed into non-coding RNAs. An elegant study identifies a function for non-coding RNA transcription in activating neighbouring genes.

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Figure 1: Ripples of transcription downstream of immediate early genes.

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Carninci, P. Non-coding RNA transcription: turning on neighbours. Nat Cell Biol 10, 1023–1024 (2008). https://doi.org/10.1038/ncb0908-1023

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