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Letter
Nature Cell Biology 10, 994–1002 (1 August 2008) | doi:10.1038/ncb1760
Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1
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Abstract
E3 ubiquitin ligases are final effectors of the enzyme cascade controlling ubiquitylation. A central issue in understanding their regulation is to decipher mechanisms of their assembly and activity.
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