News and Views
Nature Cell Biology 10, 881 - 883 (2008)
doi:10.1038/ncb0808-881
Nutrient sensing: TOR's Ragtime
Alfred J. Meijer1 & Patrice Codogno2
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Alfred J. Meijer is in the Department of Medical Biochemistry, Academic Medical Center, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
e-mail: a.j.meijer@amc.uva.nl - Patrice Codogno is in the INSERM U756, University of Paris-Sud 11, 5, rue Jean-Baptiste Clément, 92296 Châtenay-Malabry, France.
Abstract
The mammalian target of rapamycin (mTOR) controls cell growth and size. Amino acids are known to activate TOR, and Rag (Ras-related GTP-binding protein) GTPases have now been found to act as their effectors.
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