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Letter

Nature Cell Biology 10, 556–566 (1 May 2008) | doi:10.1038/ncb1718

A pathway for phagosome maturation during engulfment of apoptotic cells

Jason M. Kinchen , Kimon Doukoumetzidis , Johann Almendinger , Lilli Stergiou , Annie Tosello-Trampont , Costi D. Sifri , Michael O. Hengartner & Kodi S. Ravichandran

Removal of apoptotic cells is critical for the physiological well-being of the organism and defects in corpse removal have been linked to disease states. Genes regulating corpse recognition and internalization have been identified, but few molecules involved in the processing of internalized corpses are known.