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Letter
Nature Cell Biology 10, 415–421 (1 April 2008) | doi:10.1038/ncb1703
EB1 regulates microtubule dynamics and tubulin sheet closure in vitro
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Abstract
End binding 1 (EB1) is a plus-end-tracking protein (+TIP) that localizes to microtubule plus ends where it modulates their dynamics and interactions with intracellular organelles. Although the regulating activity of EB1 on microtubule dynamics has been studied in cells and purified systems, the molecular mechanisms involved in its specific activity are still unclear.
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