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Letter
Nature Cell Biology 10, 407–414 (1 April 2008) | doi:10.1038/ncb1702
Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation
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Abstract
During mitosis, kinetochores form persistent attachments to microtubule tips and undergo corrective detachment in response to phosphorylation by Ipl1 (Aurora B) kinase. The Dam1 complex is required to establish and maintain bi-oriented attachment to microtubule tips in vivo, and it contains multiple sites phosphorylated by Ipl1 (Refs 2, 3, 4, 5, 6, 7, 8, 9, 10).
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