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Letter
Nature Cell Biology 10, 306–313 (1 March 2008) | doi:10.1038/ncb1692
Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front
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Abstract
Eukaryotic cells advance in phases of protrusion, pause and withdrawal. Protrusion occurs in lamellipodia, which are composed of diagonal networks of actin filaments, and withdrawal terminates with the formation of actin bundles parallel to the cell edge.
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