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March 2008 Volume 10 No 3

Hypertrophy of the pericentriolar material (PCM) results in the formation of multiple daughter centrioles on the same mother. A montage is shown of triple-stained centrosomes from CHO cells arrested in S phase. SAS-6 (red) localizes to the proximal end of daughter centrioles; centrin localizes to the distal end of all centrioles (green) and the PCM is marked by g-tubulin (blue).

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