News and Views
Nature Cell Biology 10, 255 - 257 (2008)
doi:10.1038/ncb0308-255
Breaking the ties that bind centriole numbers
Jeffrey L. Salisbury1
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Jeffrey L. Salisbury is at the Tumor Biology Program and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
e-mail: salisbury@mayo.edu
Abstract
Newly formed centrioles can spring forth from clouds of pericentriolar material, violating the precise regulation of centriole counting. These observations challenge the long-standing view that centriole number is determined by the periodic activation of an assembly template thought to reside on pre-existing centrioles.
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