News and Views


Nature Cell Biology 10, 255 - 257 (2008)
doi:10.1038/ncb0308-255

Breaking the ties that bind centriole numbers

Jeffrey L. Salisbury1

  1. Jeffrey L. Salisbury is at the Tumor Biology Program and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
    e-mail: salisbury@mayo.edu


Newly formed centrioles can spring forth from clouds of pericentriolar material, violating the precise regulation of centriole counting. These observations challenge the long-standing view that centriole number is determined by the periodic activation of an assembly template thought to reside on pre-existing centrioles.

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