Ena/VASP family members have a common binding interface on their EVH1 domains for FPPPP motifs in partner proteins. The finding that Tes, a protein lacking FPPPP motifs, competes specifically for the FPPPP ligand site on Mena, provides new insights into the differential regulation of Ena/VASP proteins.
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Small, J. Facing up to Mena: Tes(ting) times for EVH1 domains. Nat Cell Biol 10, 118–120 (2008). https://doi.org/10.1038/ncb0208-118
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DOI: https://doi.org/10.1038/ncb0208-118
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