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Nature Cell Biology 10, 122 - 124 (2008)
doi:10.1038/ncb0208-122
Heads or tails: can Wnt tell which one is up?
Elly M. Tanaka1 & Gilbert Weidinger1
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Elly M. Tanaka is at the Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D-01307 Dresden, Germany and the Center for Regenerative Therapies, Dresden. Gilbert Weidinger is at the Biotechnology Center of the Technical University Dresden, Tatzberg 47, D-01307 Dresden, Germany.
e-mail: tanaka@mpi-cbg.de
e-mail: gilbert.weidinger@biotec.tu-dresden.de
Abstract
Planarian flatworms regenerate their heads and tails after amputation. It turns out that they use Wnt–
-catenin signalling to determine where the head and the tail should form.
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