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Letter

Nature Cell Biology 10, 1477–1483 (1 December 2008) | doi:10.1038/ncb1807

Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c

Allyson E. Vaughn & Mohanish Deshmukh

Neurons and cancer cells use glucose extensively, yet the precise advantage of this adaptation remains unclear. These two seemingly disparate cell types also show an increased regulation of the apoptotic pathway, which allows for their long-term survival.