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Nature Cell Biology 10, 1383–1384 (1 December 2008) | doi:10.1038/ncb1208-1383

A TRP channel-steroid marriage

Bernd Nilius & Thomas Voets

The TRP family (Fig. 1a) carries the stigma of being 'promiscuous', as its members can be tempted to gate in response to a surprising variety of stimuli, including temperature and mechanical stress, as well as various endogenous and exogenous chemicals.