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Letter
Nature Cell Biology 10, 1301–1308 (1 November 2008) | doi:10.1038/ncb1788
Actin-driven chromosomal motility leads to symmetry breaking in mammalian meiotic oocytes
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Abstract
Movement of meiosis I (MI) chromosomes from the oocyte centre to a subcortical location is the first step in the establishment of cortical polarity. This is required for two consecutive rounds of asymmetric meiotic cell divisions, which generate a mature egg and two polar bodies.
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