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Nature Cell Biology 10, 1251 - 1253 (2008)
doi:10.1038/ncb1108-1251

Bad hair days for mouse PCP mutants

Jeffrey D. Axelrod1

  1. Jeffrey D. Axelrod is in the Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA.
    e-mail: jaxelrod@stanford.edu


Mammalian hairs have characteristic patterns of orientation, with a predominantly rostral to caudal direction, occasional swirls and a high level of local correlation between hairs. A detailed new study demonstrates that the polarity of hairs derives from an underlying planar polarity of the basal epidermal cells from which hair follicles arise.

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