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Nature Cell Biology 10, 1129 - 1130 (2008)
doi:10.1038/ncb1008-1129

Stressed out? Make some modifications!

Angela Hilliker1 & Roy Parker1

  1. Angela Hilliker and Roy Parker are in the Department of Molecular and Cellular Biology and Howard Hughes Medical Institute, University of Arizona, Tucson, AZ, 85721-0106, USA.
    e-mail: rrparker@u.arizona.edu


Stress granules and processing bodies are related mRNA-containing granules implicated in controlling mRNA translation and decay. A genomic screen identifies numerous factors affecting granule formation, including proteins involved in O-GlcNAc modifications. These results highlight the importance of post-translational modifications in translational control and mRNP granule formation.

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