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Nature Cell Biology 10, 1125 - 1126 (2008)
doi:10.1038/ncb1008-1125
Pores galore for the Golgi
John H. Caldwell1 & Kathryn E. Howell1
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John H. Caldwell and Kathryn E. Howell are in the Department of Cell and Developmental Biology, University of Colorado Denver, School of Medicine, Aurora, CO 80045, USA.
e-mail: kathryn.howell@uchsc.edu
Abstract
Strict control of cisternal pH in the Golgi is required for posttranslational modification and trafficking of proteins and lipids. A chloride channel to neutralize the charge of the proton pump and to keep the Golgi membrane potential near zero has finally been discovered.
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