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Letter
Nature Cell Biology 10, 70–76 (1 January 2008) | doi:10.1038/ncb1670
Kif3a constrains |[beta]|-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms
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Abstract
Primary cilia are microtubule-based organelles involved in signal transduction and project from the surface of most vertebrate cells. Proteins that can localize to the cilium, for example, Inversin and Bardet-Biedl syndrome (BBS) proteins, are implicated in both β-catenin-dependent and -independent Wnt signalling.
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