News and Views
Nature Cell Biology 10, 3 - 5 (2008)
doi:10.1038/ncb0108-3
Motor-cargo release: CaMKII as a traffic cop
Shabeen Ally1, Amber L. Jolly1 & Vladimir I. Gelfand1
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Shabeen Ally, Amber L. Jolly and Vladimir I. Gelfand are at the Department of Cell and Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611.
e-mail: vgelfand@northwestern.edu
Abstract
The spatial and temporal regulation of motor-based transport is essential to ensure precise cargo delivery in all cell types. New light has been shed on mechanisms controlling cargo–motor interactions, with the finding that NMDA-cargo is released from KIF17 kinesin following motor phosphorylation by CaMKII near the synapse.
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