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Nature Cell Biology 1, E152–E154 (1 October 1999) | doi:10.1038/14105

Dendritic cells spill the beans

Colin Watts

Antigens taken up into cells by endocytosis are not usually presented on class I MHC molecules to cytotoxic T cells. But there are good reasons to allow professional antigen-presenting cells to do this, and it seems that dendritic cells of the immune system have an efficient mechanism in place for achieving such presentation.