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Nature Cell Biology 1, E142 (1 October 1999) | doi:10.1038/14092

Putting actin organization on a pedestal

Barbara Marte

Like many other pathogens, enteropathogenic Escherichia coli (EPEC), a diarrhoea-causing bacterium responsible for the death of millions in developing countries, has evolved some cunning tricks for infecting host cells: it subverts normal cellular processes for its own ends. Attempts to understand this molecular trickery shed light on not only the pathogenic processes of EPEC infection but also the underlying cellular machinery.