Focus on Membrane Traffic abstract


Nature Cell Biology 1, E154 - E155 (1999)
doi:10.1038/14107

Protein folding in vivo: the importance of ribosomes

Thomas O. Baldwin1

  1. Thomas O. Baldwin is in the Biochemistry Department, The University of Arizona, PO Box 210088, Tucson, Arizona 85721-0088, USA.

Correspondence to: Thomas O. Baldwin1 e-mail: e-mail: tbaldwin@u.arizona.edu


The folding of proteins into their native conformation is more favourable kinetically if it occurs at the same time as protein synthesis, but there are few examples of such co-translational folding. The folding of the Semliki Forest virus capsid protein is one example.

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