Focus on Membrane Traffic abstract
Nature Cell Biology 1, E152 - E154 (1999)
doi:10.1038/14105
Dendritic cells spill the beans
Colin Watts1
- Colin Watts is in the Department of Biochemistry, Wellcome Trust Building, University of Dundee, Dundee DD1 5EH , UK.
Correspondence to: Colin Watts1 e-mail: e-mail: c.watts@dundee.ac.uk
Abstract
Antigens taken up into cells by endocytosis are not usually presented on class I MHC molecules to cytotoxic T cells. But there are good reasons to allow professional antigen-presenting cells to do this, and it seems that dendritic cells of the immune system have an efficient mechanism in place for achieving such presentation.
