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Nature Cell Biology 1, E115–E117 (1 September 1999) | doi:10.1038/12942

Close encounters of the LIM-kinase

Jonathan Chernoff

During cell movement, new actin structures are formed, under the orders of the small GTPase Rac. One of Rac|[rsquo]|s orders is to inhibit the depolymerization of existing actin filaments. A chain of events from Rac to the inhibition of actin depolymerization has now been forged.