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Nature Cell Biology 1, E113–E115 (1 September 1999) | doi:10.1038/12939
The mesh hypothesis of Golgi dynamics
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Abstract
The GTP-binding protein ARF induces the recruitment to the Golgi membrane of kinases that catalyse the synthesis of the lipid phosphatidylinositol-4,5-bisphosphate. This lipid acts as a binding site for certain actin-binding proteins, which may change the Golgi membrane skeleton to a form that allows membrane traffic.
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