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Nature Cell Biology 1, E117–E119 (1 September 1999) | doi:10.1038/12944
Wounding Smad
Abstract
TGF-|[bgr]| is a cytokine that enhances wound healing, a process involving diverse TGF-|[bgr]|-responsive cell types. Mice with a deletion of the Smad3 gene exhibit an increased rate of wound healing. The lack of Smad3 seems to modify the cellular response to TGF-|[bgr]| and may suggest an intriguing molecular basis to this process.
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