News and Views abstract
Nature Cell Biology 1, E125 - E127 (1999)
doi:10.1038/12956
Meiosis: Rec8 is the reason for cohesion
Chatanika Stoop-Myer1 & Angelika Amon1
- Chatanika Stoop-Myer and Angelika Amon are at the Center for Cancer Research, Massachusetts Institute of Technology, 40 Ames Street E17-233, Cambridge, Massachusetts 02139, USA.
Correspondence to: Angelika Amon1 e-mail: angelika@mit.edu
Abstract
During meiosis, sister chromatids produced by chromosome duplication are held together by Rec8, a meiosis-specific cohesion protein. Rec8 joins the whole length of the sister chromatids together, and, as meiosis proceeds, is lost in a stepwise manner that correlates with the loss of sister-chromatid cohesion.
