News and Views abstract
Nature Cell Biology 1, E115 - E117 (1999)
doi:10.1038/12942
Close encounters of the LIM-kinase
Jonathan Chernoff1
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Jonathan Chernoff is at the Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, Pennsylvania 19111, USA.
e-mail: J_Chernoff@fccc.edu
Abstract
During cell movement, new actin structures are formed, under the orders of the small GTPase Rac. One of Rac's orders is to inhibit the depolymerization of existing actin filaments. A chain of events from Rac to the inhibition of actin depolymerization has now been forged.
