News and Views abstract
Nature Cell Biology 1, E89 - E91 (1999)
doi:10.1038/12085
Knocking signalling out of the dystrophin complex
- David S. Bredt is in the Department of Physiology, University of California at San Francisco, San Francisco, California 94143, USA
- and University of California at San Francisco School of Medicine, 513 Parnassus Avenue, San Francisco, California 94143-0444, USA.
Correspondence to: David S. Bredt1,2 e-mail: bredt@itsa.ucsf.edu
Abstract
Mice lacking dystrobrevin, a dystrophin-associated protein, exhibit a new form of muscular dystrophy in which the integrity of muscle fibres is maintained, but a component of muscle-cell signalling is disrupted.
