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Nature Cell Biology 1, E42–E44 (1 June 1999) | doi:10.1038/10036

Asymmetry across species

Yuh-Nung Jan & Lily Yeh Jan

In both worms and flies, asymmetric cell divisions involve the protein Bazooka/PAR-3, which is required for the asymmetric segregation of cell-fate determinants. However, differential distribution of a determinant between daughter cells may be achieved by different means in alternative developmental settings.