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Review
Nature Cell Biology 1, E47–E53 (1 June 1999) | doi:10.1038/10039
Regulation of the APC and the exit from mitosis
Abstract
The events of late mitosis, from sister-chromatid separation to cytokinesis, are governed by the anaphase-promoting complex (APC), a multisubunit assembly that triggers the ubiquitin-dependent proteloysis of key regulatory proteins. An intricate regulatory network governs APC activity and helps to ensure that late mitotic events are properly timed and coordinated.
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