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Nature Cell Biology 1, E40–E42 (1 June 1999) | doi:10.1038/10034

Hidden powers of the mitochondria

Emad S. Alnemri

The intermembrane space of mitochondria is home to several potentially lethal proteins, including pro-apoptotic caspases. The observation that caspase-9 moves from mitochondria into the nucleus on the induction of apoptosis provides this caspase with a possible new role.