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Nature Cell Biology 1, E33–E35 (1 June 1999) | doi:10.1038/10026

How BAD phosphorylation is good for survival

Julian Downward

BAD is a pro-apoptotic member of the Bcl-2 family that is tightly regulated by survival factors. Several major signalling pathways influence cell death through their direct effects on the phosphorylation state of BAD.