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Nature Cell Biology 1, E29–E31 (1 June 1999) | doi:10.1038/10020

Rocket-based motility: a universal mechanism?

Laura M. Machesky

Similarities between actin polymerization at the leading edges of motile mammalian cells and the motile actin tail of the bacterium Listeria monocytogenes are centred on the Arp2/3 complex. Eukaryotic cells use multiple pathways to modulate actin polymerization, while Listeria short-circuits these pathways to produce constitutive actin polymerization.