Review abstract
Nature Cell Biology 1, E47 - E53 (1999)
doi:10.1038/10039
Regulation of the APC and the exit from mitosis
David O. Morgan1
Abstract
The events of late mitosis, from sister-chromatid separation to cytokinesis, are governed by the anaphase-promoting complex (APC), a multisubunit assembly that triggers the ubiquitin-dependent proteloysis of key regulatory proteins. An intricate regulatory network governs APC activity and helps to ensure that late mitotic events are properly timed and coordinated.
- Department of Physiology, University of California , San Francisco, California 94143-0444, USA
Correspondence to: David O. Morgan1 e-mail: dmorgan@cgl.ucsf.edu
