News and Views abstract
Nature Cell Biology 1, E44 - E45 (1999)
doi:10.1038/10037
Caspase activity sows the seeds of neuronal death
Junying Yuan1 & Bruce A. Yankner2
- Junying Yuan is in the Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA.
- Bruce A. Yankner is in the Department of Neurology, Harvard Medical School, and Children's Hospital, Enders 260, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.
Correspondence to: Junying Yuan1 e-mail: jyuan@hms.harvard.edu
Abstract
Caspases, proteases involved in programmed cell death, may have a role in Alzheimer's and Huntington's diseases. Localized caspase activation and apoptosis may be linked to the initiation of such chronic neurodegenerative diseases.
