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Nature Cell Biology 1, E42 - E44 (1999)
doi:10.1038/10036

Asymmetry across species

Yuh-Nung Jan1 & Lily Yeh Jan1

  1. Yuh-Nung Jan and Lily Yeh Jan are at theHoward Hughes Medical Institute, Departments of Physiology and Biochemistry, Box 0725, UCSF, San Francisco, California 94143-0725, USA.

Correspondence to: Yuh-Nung Jan1 e-mail: ynjan@itsa.ucsf.edu


In both worms and flies, asymmetric cell divisions involve the protein Bazooka/PAR-3, which is required for the asymmetric segregation of cell-fate determinants. However, differential distribution of a determinant between daughter cells may be achieved by different means in alternative developmental settings.

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