News and Views abstract
Nature Cell Biology 1, E40 - E42 (1999)
doi:10.1038/10034
Hidden powers of the mitochondria
Emad S. Alnemri1
- Emad S. Alnemri is at the Kimmel Cancer Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Correspondence to: Emad S. Alnemri1 e-mail: E_Alnemri@lac.jci.tju.edu
Abstract
The intermembrane space of mitochondria is home to several potentially lethal proteins, including pro-apoptotic caspases. The observation that caspase-9 moves from mitochondria into the nucleus on the induction of apoptosis provides this caspase with a possible new role.
