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Nature Cell Biology 1, E29 - E31 (1999)
doi:10.1038/10020
Rocket-based motility: a universal mechanism?
Laura M. Machesky1
- Laura M. Machesky is in the Department of Biochemistry, University of Birmingham, Birmingham B15 2TT, UK.
Correspondence to: Laura M. Machesky1 e-mail: l.m.machesky@bham.ac.uk
Abstract
Similarities between actin polymerization at the leading edges of motile mammalian cells and the motile actin tail of the bacterium Listeria monocytogenes are centred on the Arp2/3 complex. Eukaryotic cells use multiple pathways to modulate actin polymerization, while Listeria short-circuits these pathways to produce constitutive actin polymerization.
