An interdisciplinary forum: integrating new horizons - ppE1 - E2

doi:10.1038/8948

Full Text - An interdisciplinary forum: integrating new horizons | PDF (161 KB) - An interdisciplinary forum: integrating new horizons

Peeping at the vesicle kiss - ppE3 - E4

Riccardo Fesce & Jacopo Meldolesi

doi:10.1038/8950

Abstract - | Full Text - Peeping at the vesicle kiss | PDF (159 KB) - Peeping at the vesicle kiss

Skipping into the E2F1-destruction pathway - ppE5 - E7

J. Wade Harper & Stephen J. Elledge

doi:10.1038/8952

Abstract - | Full Text - Skipping into the E2F1-destruction pathway | PDF (207 KB) - Skipping into the E2F1-destruction pathway

The strain of copper on the brain - pE7

Harriet Coles

doi:10.1038/8955

Full Text - The strain of copper on the brain | PDF (151 KB) - The strain of copper on the brain

New twists for dynamin - ppE8 - E9

Regis B. Kelly

doi:10.1038/8957

Abstract - | Full Text - New twists for dynamin | PDF (167 KB) - New twists for dynamin

What goes up must come down - ppE10 - E11

Sally J. Leevers

doi:10.1038/8960

Abstract - | Full Text - What goes up must come down | PDF (148 KB) - What goes up must come down

A method for movement - pE12

Sally H. Zigmond

doi:10.1038/8962

Abstract - | Full Text - A method for movement | PDF (142 KB) - A method for movement

A unifying concept: the history of cell theory - ppE13 - E15

Paolo Mazzarello

doi:10.1038/8964

Abstract - | Full Text - A unifying concept: the history of cell theory | PDF (290 KB) - A unifying concept: the history of cell theory

Transport-vesicle targeting: tethers before SNAREs - ppE17 - E22

Suzanne R. Pfeffer

doi:10.1038/8967

Abstract - | Full Text - Transport-vesicle targeting: tethers before SNAREs | PDF (243 KB) - Transport-vesicle targeting: tethers before SNAREs

Spatial control of coated-pit dynamics in living cells - pp1 - 7

Ibragim Gaidarov, Francesca Santini, Robin A. Warren & James H. Keen

doi:10.1038/8971

Abstract - | Full Text - Spatial control of coated-pit dynamics in living cells | PDF (496 KB) - Spatial control of coated-pit dynamics in living cells | Supplementary information

Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells - pp8 - 13

Ruth Kroschewski, Alan Hall & Ira Mellman

doi:10.1038/8977

Abstract - | Full Text - Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells | PDF (1,106 KB) - Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells

Interaction between ubiquitin–protein ligase SCF^SKP2 and E2F-1 underlies the regulation of E2F-1 degradation - pp14 - 19

A. Marti, C. Wirbelauer, M. Scheffner & W. Krek

doi:10.1038/8984

Abstract - | Full Text - Interaction between ubiquitin–protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation | PDF (355 KB) - Interaction between ubiquitin–protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

See also: News and Views by Harper & Elledge

Nucleolar Arf sequesters Mdm2 and activates p53 - pp20 - 26

Jason D. Weber, Laura J. Taylor, Martine F. Roussel, Charles J. Sherr & Dafna Bar-Sagi

doi:10.1038/8991

Abstract - | Full Text - Nucleolar Arf sequesters Mdm2 and activates p53 | PDF (419 KB) - Nucleolar Arf sequesters Mdm2 and activates p53

Nucleotide-dependent conformational changes in dynamin: evidence for a mechanochemical molecular spring - pp27 - 32

Michael H. B. Stowell, Bruno Marks, Patrick Wigge & Harvey T. McMahon

doi:10.1038/8997

Abstract - | Full Text - Nucleotide-dependent conformational changes in dynamin: evidence for a mechanochemical molecular spring | PDF (461 KB) - Nucleotide-dependent conformational changes in dynamin: evidence for a mechanochemical molecular spring

See also: News and Views by Kelly

Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis - pp33 - 39

Kohji Takei, Vladimir I. Slepnev, Volker Haucke & Pietro De Camilli

doi:10.1038/9004

Abstract - | Full Text - Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis | PDF (1,702 KB) - Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis

See also: News and Views by Kelly

High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism - pp40 - 44

Eva Alés, Lucía Tabares, Juan M. Poyato, Vicente Valero, Manfred Lindau & Guillermo Alvarez de Toledo

doi:10.1038/9012

Abstract - | Full Text - High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism | PDF (267 KB) - High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism

See also: News and Views by Fesce & Meldolesi

Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts - pp45 - 50

Clare M. Waterman-Storer, Rebecca A. Worthylake, Betty P. Liu, Keith Burridge & E.D. Salmon

doi:10.1038/9018

Abstract - | Full Text - Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts | PDF (761 KB) - Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts | Supplementary information

See also: News and Views by Zigmond

Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos - pp51 - 54

David J. Sharp, Kristina R. Yu, John C. Sisson, William Sullivan & Jonathan M. Scholey

doi:10.1038/9025

Abstract - | Full Text - Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos | PDF (1,200 KB) - Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos

Strain-specific prion-protein conformation determined by metal ions - pp55 - 59

Jonathan D.F. Wadsworth, Andrew F. Hill, Susan Joiner, Graham S. Jackson, Anthony R. Clarke & John Collinge

doi:10.1038/9030

Abstract - | Full Text - Strain-specific prion-protein conformation determined by metal ions | PDF (258 KB) - Strain-specific prion-protein conformation determined by metal ions

See also: News and Views by Coles

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases - pp60 - 67

Ralph Hoessel, Sophie Leclerc, Jane A. Endicott, Martin E. M. Nobel, Alison Lawrie, Paul Tunnah, Maryse Leost, Eve Damiens, Dominique Marie, Doris Marko, Ellen Niederberger, Weici Tang, Gerhard Eisenbrand & Laurent Meijer

doi:10.1038/9035

Abstract - | Full Text - Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases | PDF (705 KB) - Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases | Supplementary information

Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages - pp69 - 71

Bart Vanhaesebroeck, Gareth E. Jones, William E. Allen, Daniel Zicha, Roya Hooshmand-Rad, Carol Sawyer, Claire Wells, Michael D. Waterfield & Anne J. Ridley

doi:10.1038/9045

Full Text - Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages | PDF (205 KB) - Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages | Supplementary information

Endocytic vesicles move at the tips of actin tails in cultured mast cells - pp72 - 74

Christien J. Merrifield, Stephen E. Moss, Christoph Ballestrem, Beat A. Imhof, Günter Giese, Ilse Wunderlich & Wolfhard Almers

doi:10.1038/9048

Full Text - Endocytic vesicles move at the tips of actin tails in cultured mast cells | PDF (479 KB) - Endocytic vesicles move at the tips of actin tails in cultured mast cells | Supplementary information