Nature Cell Biology - ncb Current issue : November 2008 - Vol 10 No 11
Latest content
Advance online publication
Force reconstruction in migration
Article by JiDanuser and colleagues reconstruct intracellular force levels in cell protrusions and correlate these with F-actin flow. Cell adhesion is regulated at the interface between vinculin and integrin and a putative feedback is revealed between increase in tension and F-actin assembly.
Advance online publication
Spreading brain cancer
Letter by SkogBreakefield, Skog and colleagues show that human glioblastoma cells release microvesicles containing a diverse set of proteins, miRNAs and mRNAs, which can be taken up by normal host cells that translate the mRNA. Glioma-derived microvesicles carrying the specific tumour markers EGFRvIII and miRNA-21 promote cell proliferation and may serve as a diagnostic tool.
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Structural Genomics Knowledgebase
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