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Please quote Nature Biotechnology as the source of these items.

The April 2006 issue of Nature Biotechnology is available online.

 April 2006 Previous Next

Genetically modified pork - with healthier fat

Nature Biotechnology pp 435 - 436

Scientists have generated piglets with higher levels of omega-3 fatty acids, a type of fat known to be beneficial to human health. The fat is found naturally - primarily in fish oils - but if omega-3 pigs reach the supermarket, it would be available at higher levels in bacon and other pork products. Yifan Dai, Randall Prather and colleagues report the production of the omega-3 piglets in April's Nature Biotechnology.

To increase the omega-3 fatty acid content in pork, the researchers generated piglets that contain an extra gene. The protein encoded by this gene converts another type of fatty acid into omega-3 fatty acids. Additional research is needed before omega-3 pigs could be considered for human consumption. Questions for further study include the long-term health of the pigs, whether omega-3 fatty acid levels will remain high when the animals reach adulthood, and how the meat tastes.

The demand for omega-3 fatty acids has increased considerably in recent years because they have demonstrated benefits in a range of chronic inflammatory diseases, such as cardiovascular disease, rheumatoid arthritis and diabetes. As fish stocks are declining and can be contaminated with heavy metals, new dietary sources of omega-3 fatty acids are desirable.


Generation of cloned transgenic pigs rich in omega-3 fatty acids pp 435 - 436
Liangxue Lai, Jing X Kang, Rongfeng Li, Jingdong Wang, William T Witt, Hwan Yul Yong, Yanhong Hao, David M Wax, Clifton N Murphy, August Rieke, Melissa Samuel, Michael L Linville, Scott W Korte, Rhobert W Evans, Thomas E Starzl, Randall S Prather & Yifan Dai
Published online: 26 March 2006 | doi:10.1038/nbt1198
Abstract | Full text | PDF | Supplementary Information
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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