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Volume 35 Issue 5, May 2017

Artist's impression of a base editor. K. Kim et al. (p 435) show that base-editing can efficiently create genetically modified mice, and Shimatani et al. (p 441) and Zong et al. (p 438) base-edit the genomes of crop plants. D. Kim et al. (p 475) present a genome-wide analysis of the specificity of a base editor. Image credit: Younghee Lee, CUBE3D graphic

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  • The hegemony of the CRISPR system as a gene-editing therapy is not as assured as its use as a tool in basic research.

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  • Our personal ecosystem of microbes is shed on everything we touch and everyplace we go. Charles Schmidt reports on efforts to harness this information to improve human health and activity.

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  • Biotechnology and chemistry researchers look to the patent literature as a source of technical information more than researchers in other fields, and few researchers are deterred from reading patents by concerns about enhanced legal liability.

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