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Yarrowia lipolytica colonies growing on YPD agar at 28 °C. Qiao et al. (p 173) improve the productivity and yield of carbohydrate-to-lipid conversion in this industrial yeast by redox engineering. Image credit: Hortensia Rico, Department of Microbiology, University of Valencia, Spain.
Despite last year's sharp decline in approvals, registrations of two RNA drugs offer a window into the current state and possible future of drug development. Looking forward, the sector seeks greater clarity on the new presidential administration's priorities and the impact of new healthcare legislation. Chris Morrison reports.
The global effects of epistasis on protein and RNA function are revealed by an unsupervised model of amino acid co-conservation in evolutionary sequence variation.
