Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Systematic discovery of probiotics

Systems-level modeling of the gut microbiota uncovers a candidate bacteriotherapy for Clostridium difficile.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Systematic candidate bacteriotherapy selection.

References

  1. Buffie, C.G. et al. Nature doi:10.1038/nature13828 (22 October 2014).

  2. Borody, T.J. et al. J. Clin. Gastroenterol. 38, 475–483 (2004).

    Article  Google Scholar 

  3. van Nood, E. et al. N. Engl. J. Med. 368, 407–415 (2013).

    Article  CAS  Google Scholar 

  4. Tvede, M. & Rask-Madsen, J. Lancet 1, 1156–1160 (1989).

    Article  CAS  Google Scholar 

  5. Petrof, E.O. et al. Microbiome 1, 3 (2013).

    Article  Google Scholar 

  6. Lawley, T.D. et al. PLoS Pathog. 8, e1002995 (2012).

    Article  CAS  Google Scholar 

  7. Reeves, A.E., Koenigsknecht, M.J., Bergin, I.L. & Young, V.B. Infect. Immun. 80, 3786–3794 (2012).

    Article  CAS  Google Scholar 

  8. Theriot, C.M. et al. Nat. Commun. 5, 3114 (2014).

    Article  Google Scholar 

  9. Wilson, K.H., Kennedy, M.J. & Fekety, F.R. J. Clin. Microbiol. 15, 443–446 (1982).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Trevor D Lawley.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Forster, S., Lawley, T. Systematic discovery of probiotics. Nat Biotechnol 33, 47–48 (2015). https://doi.org/10.1038/nbt.3111

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt.3111

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing