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Neuron- and glia-like cells derived from induced pluripotent stem cells promise tractable, individualized human models of Alzheimer's, Parkinson's and amyotrophic lateral sclerosis. Ken Garber explores the considerable challenges of recreating such diseases in the laboratory.
The holy grail of printed human organs remains a long way off, but commercial efforts to print simple structures and tissues are forging ahead. Gunjan Sinha reports.
Will freedom to research and innovate be restricted as the induced pluripotent stem cell field advances toward the clinic, or are concerns premature within a rapidly changing ecosystem?
Immunology is on the cusp of a 'big data'–driven breakthrough, but strategies for standardizing and sharing high-dimensional data from independent laboratories are needed to ensure that data support the formation of new and robust hypotheses.
Laszlo et al. demonstrate sequence alignment, and proof-of-concept organism identification, genome assembly and polymorphism detection from nanopore analysis of natural DNA.
