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June 2014 Volume 32 No 6

Illustration of diverse RNA hairpins (yellow and orange) binding to coat proteins (blue) inside an assembling MS2A viral capsid. Buenrostro et al. repurpose an Illumina sequencer (yielding raw black and white fluorescence images in background) for high-throughput measurement of RNA-protein binding affinities to study structure-function relationships (represented by the hexagonal RNA hairpin diagrams) (p 562). Credit: Carlos L. Araya

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