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Making biology transparent

The molecular and cellular architecture of the organs in a whole mouse is revealed through optical clearing.

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Figure 1: Whole-organ clearing with perfusion-assisted agent release in situ.

Marina Corral Spence/Nature Publishing Group

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Correspondence to Burkhard Höckendorf, Luke D Lavis or Philipp J Keller.

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Höckendorf, B., Lavis, L. & Keller, P. Making biology transparent. Nat Biotechnol 32, 1104–1105 (2014). https://doi.org/10.1038/nbt.3061

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