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Global mapping of cancer gene expression changes to the human metabolic network. Hu et al. find substantial heterogeneity in how cellular metabolism is reprogrammed across 22 cancers (p 522). Credit: Jie Hu and Dennis Vitkup using the iPath tool.
To prevent a popular backlash against the spiraling prices of US prescription medicines, industry needs to do more to address out-of-pocket expenses for patients.
The field of induced pluripotent stem cells is barely seven years old, but already three groups are close to launching clinical trials. Ken Garber looks into the prospects and perils.
Delineating four categories of field-evolved resistance of pests to Bt crops, through analysis of 77 studies carried out in five continents from 1996 to 2012, should inform future pest management strategies.
Zwitterionic hydrogels may be a useful biocompatible material, as they resist collagen capsule formation yet promote angiogenesis after implantation in mice.
