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Volume 30 Issue 8, August 2012

Artistic rendering of the process of reverse-engineering a jellyfish. Illustrated clockwise from the top, a juvenile Aurelia sp. is analyzed on the exterior (brightfield image) and interior (green, F-actin muscle stain; red, α-tubulin neuron stain; blue, DAPI nuclear stain), and the results are translated to micropatterning of rat cardiomyocytes on silicone polymer. The animal/construct diameter is ~9 mm (p 792). Credit: Janna Nawroth

Volume 30 Issue 8

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Editorial

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News

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Data Page

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News Feature

  • Tension between practitioners who believe autologous stem cells should be considered a service and the FDA, which considers some of them biologics, has come to a head in recent months. Laura DeFrancesco investigates.

    • Laura DeFrancesco
    News Feature
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Bioentrepreneur

  • A serial entrepreneur learns that the world's most exciting, groundbreaking technology is pointless if it is unable to address an urgent and relevant need.

    • Tillman Gerngross
    Bioentrepreneur
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Correspondence

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Feature

  • The financial performance of the public biotech sector was remarkably buoyant last year, but a few worrying clouds hover on the horizon.

    • Brady Huggett
    • Riku Lähteenmaki
    Feature
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Patents

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News & Views

  • Stretching DNA molecules in nanochannels allows structural and copy-number variations to be visualized like beads on a string.

    • Yael Michaeli
    • Yuval Ebenstein
    News & Views

  • Sequencing of the tomato genome reveals key events in the evolution of fruit size, texture, flavor and nutritional quality.

    • Todd P Michael
    • Rob Alba
    News & Views
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Research Highlights

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Profile

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Article

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Letter

  • Nawroth et al. combine rat cardiomyocytes and silicone polymer to make a jellyfish replica that mimics the propulsive behavior of its live counterpart. The design principles guiding this feat may facilitate tissue engineering of muscular organs.

    • Janna C Nawroth
    • Hyungsuk Lee
    • Kevin Kit Parker
    Letter

  • Sequencing a genome and identifying genetic markers lays the groundwork for genome-wide association studies, but can be difficult to achieve for polyploid species. Harper et al. present an approach for performing association studies using genetic maps and markers generated from transcriptome sequencing data alone and apply it to the polyploid crop Brassica napus.

    • Andrea L Harper
    • Martin Trick
    • Ian Bancroft
    Letter
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Careers and Recruitment

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